Seattle Seahawks vs San Francisco 49ers NFL Week 18 Tips & Predictions
An all-time divisional clash headlines Week 18 as the Seattle Seahawks travel to Levi’s Stadium to face the San Francisco 49ers with the NFC’s top seed on the line.
Both teams enter in elite form, but San Francisco hold the edge at home, riding momentum, crowd noise and a quarterback playing at an MVP-adjacent level.
Match Details: Seahawks vs 49ers
- Competition: NFL 2025 - Week 18
- Match: Seattle Seahawks vs San Francisco 49ers
- Date: Sunday, 4 January 2026
- Kick-off: 12:00 PM AEDT
- Venue: Levi’s Stadium
Best Betting Tips - Seahawks vs 49ers
San Francisco 49ers - Moneyline
San Francisco have won seven of the last eight meetings and are unbeaten at home in big-spot games this season. Brock Purdy continues to deliver late, and the 49ers’ offence has proven more reliable in pressure moments.
Under 49.5 Total Points
Despite elite offensive rankings, recent matchups between these sides have trended Under. With playoff implications and conservative fourth-quarter play expected, this shapes as a tighter contest than the raw totals suggest.
Brock Purdy Over 251.5 Passing Yards
Seattle’s secondary has allowed 250+ passing yards in consecutive weeks. Purdy threw for 277 yards against the Seahawks in Week 1 and has gone Over this line in three straight games.
Zach Charbonnet Anytime Touchdown
Seattle’s red-zone offence flows through the ground game. Charbonnet has scored in two straight games and was the Seahawks’ only touchdown scorer in the Week 1 matchup.
Key Matchup to Watch
49ers Passing Game vs Seahawks Secondary
San Francisco continue to attack the middle of the field aggressively, even on late downs. Seattle’s pass defence ranks outside the top ten and has struggled to contain sustained drives against elite quarterbacks.